Announced positive top-line results from a pivotal today.

One of Restanza’s major differentiating advantages, and a key characteristic that has attracted US authorities interest, is definitely its demonstrated breadth of activity against many lethal pathogens. Related StoriesAntibiotic level of resistance potentially threatens the basic safety and efficacy of surgical treatments and immunosuppression therapiesUnlocking the genes behind antibiotic resistance: an interview with Professor RomesbergNovel mathematical method may help reduce development of antibiotic-resistant bacteriaTularemia can be a bacterial disease typically transmitted to humans through contact with infected rodents or rabbits or through bugs that carry Francisella tularensis, the causative agent of tularemia, which is usually classified by the Centers for Disease Control as a Category A Bioterrorism Agent and is normally prioritized by the Section of Defense and Division of Health and Human Services among the most significant biological weapons, along with anthrax and plague.Any remaining variations in the frequency of nodal metastasis could be accounted for by possibility or by late nodal recurrences still pending in the observation group.31,32 These data indicate that essentially all metastases detected by sentinel-node biopsy eventually could have become clinically evident if not removed. Despite the consistent strength of the data from the MSLT-I, there’s been some reluctance to simply accept the benefits of comparisons between node-positive patients in the biopsy group and those in the observation group, because of concern about ascertainment bias. Latent-subgroup analysis methods were used to address this statistical consideration.