Insulin is definitely a hormone that regulates blood sugar; type 2 diabetes evolves when the body becomes less attentive to insulin – – causing degrees of both hormone and blood sugars to soar. Obesity is a key risk factor for type 2 diabetes, but body fat distribution can be important: Individuals who carry their weight around the center are particularly vulnerable to diabetes, along with heart disease. ‘Differences in KLF14 variants do not affect general body weight,’ Small described. ‘They’re only related to surplus fat distribution.’ Saturday at the annual meeting of the American Society of Human Genetics Little was to provide her findings, in Baltimore. Research presented at meetings should be seen as preliminary until published in a peer-examined journal.Robert B. Nadelman, M.D.D., Priyanka Mukherjee, B.S., Dionysios Liveris, Ph.D., John Nowakowski, M.D., Donna McKenna, A.N.P., Dustin Brisson, Ph.D., Denise Cooper, B.S., Susan Bittker, M.S., Gul Madison, M.D., Diane Holmgren, R.N., Ira Schwartz, Ph.D., and Gary P. Wormser, M.D.: Differentiation of Reinfection from Relapse in Recurrent Lyme Disease Erythema migrans, the most typical scientific manifestation of Lyme disease, is because of cutaneous an infection with Borrelia burgdorferi .1 Erythema migrans can disappear and relapse in untreated patients,2 or it may transiently improve and worsen in those who receive antibiotics that lack activity from this bacterium.3 A number of recurrences of this skin lesion may also develop in patients after appropriate antibiotic treatment; recurrence was observed in around 15 percent of individuals who were adopted for 5 years in one research conducted in the usa.4 Available medical and epidemiologic data suggest that most recurrences following recommended courses of antibiotic therapy will be the result of a new tick-transmitted infection with B.