Another 21 % of the women self-reported one risk aspect, yet still that they had no perceived risk. Only 29 % of the populace acknowledged and identified themselves as having true risk for a future heart attack. A small part of the survey participants – – 14 % – – said no risk was acquired by them elements, and 4 % had suffered a previous coronary attack. The survey also uncovered some early indicators for heart disease within the prospective group. They are: – – 55 % of ladies said they were at least 20 pounds overweight – – 44 % of females said they possess a family group history of heart attacks – – 32 % of women reported high blood circulation pressure and/or raised chlesterol – – 13 % of women smoke – – ten % of females have diabetes ‘Our ideal challenge in preventing heart disease and heart attacks is certainly changing behaviors,’ explains Meg Durbin, M.D., a family group practice physician with Palo Alto Medical Foundation.The extension study evaluated more than 1,200 females aged 68 years or older. After three years of therapy, participants had been randomized to either receive an Aclasta infusion or an annual placebo infusion for extra three years. The primary endpoint of the analysis was the %age alter in the BMD at the femoral neck at year six vs. Year three. Secondary endpoints included evaluation of BMD at additional sites, fractures, adjustments in bone turnover markers and overall protection. The incidence of adverse events was comparable between groups.